Postdoc Position at Imperial College London

Applications are invited for a postdoc position in molecular biology to join Imperial College London. The funds for this fellowship are available for 18 months. The deadline to apply is October 08, 2019.

The Cellular and Molecular Biomechanics Laboratory - CMBL (http://biomechanicalregulation-lab.org/) is a multidisciplinary research group that combines cellular and molecular biology tools with biophysical,bioengineering and nanotechnology approaches to investigate how mechanical stimuli regulate the behaviour of cells and molecules. CMBL is hosted by the Department of Bioengineering at Imperial College London. The group has national and international collaborations in a broad range of disciplines ranging from proteomics and biophysics to cancer biology.

The post is sponsored by the European Research Council grant MechanoGPER to investigate the effects of G protein-coupled estrogen receptor (GPER) activators on cancer and stromal cells. Within the group of stromal cells, the study will focus on: (i) pancreatic stellate cells to target fibrosis, and (ii) tumour associated macrophages, which are known to have tumour-promoting properties. Following this, the project will investigate the efficacy of self-assembling peptide hydrogels to deliver these compounds to pancreatic organoids. The Research Associate will be expected to assist submission of publications to refereed journals and the writing of external research funding application.

You will be responsible to lead the project in the emerging and growing field of mechanotransduction. You will use a broad range of techniques including cell and molecular biology, biophysical techniques, and immunofluorescence. You will establish collaborations with other team members and external collaborators including clinicians. You will also supervise MRes students that will work in subprojects derived from the MechanoGPER project.

You will have a PhD (or equivalent) in an area pertinent to the research subject (i.e. Bioengineering or similar). Previous experience in GPER mechanosignalling is essential. Experience using biophysical techniques such as magnetic tweezers and elastic pillars is highly desirable.

This is a fixed term position for 18 months in the first instance.

Informal queries relating to the position should be directed to Dr Armando del Rio Hernandez at a.del-rio-hernandez@imperial.ac.uk.

Our preferred method of application is via our website. Please click "APPLY NOW" to go through to the online application form. Should you have any queries regarding the application process please contact: Jo Adam (i.adam@imperial.ac.uk)

Deadline: October 08, 2019
Apply Link:http://tinyurl.com/y5yrbvpy

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