Postdoctoral Postdoc Position Idss at University of North Carolina Chapel Hill

Applications are invited for a postdoctoral position in molecular biology to join University of North Carolina Chapel Hill. This position is available for two years in the first instance. Applications should be submitted as soon as possible.

The Institute for Drug Safety Sciences (IDSS) located in Research Triangle Park, NC is seeking outstanding and motivated candidates to lead studies exploring the utility of hepatocyte-derived exosomes (HDEs) to improve the prediction and mechanistic understanding of idiosyncratic drug-induced liver injury (IDILI). Founded in 2008, the IDSS has quickly become one of the world's leading research enterprises in drug safety. Under the direction of Dr. Paul Watkins, an internationally recognized expert in drug safety, the IDSS has focused on developing innovative approaches to investigate the underlying mechanisms and mitigate risk of rare or "idiosyncratic" toxicities that are often not discovered until late in clinical development. The IDSS has fostered international alliances between the pharmaceutical industry, academia, and the FDA. Graduates of the IDSS training program are quickly recruited to jobs in all three sectors. The IDSS is part of the Division of Pharmacotherapy and Experimental Therapeutics within the UNC Eshelman School of Pharmacy. The School of Pharmacy is the oldest of the health sciences academic programs at UNC Chapel Hill and is the top ranked pharmacy school in the US. The post-doctoral position is within the IDSS translational pharmacogenomics group, led by Dr. Merrie Mosedale. Responsibilities will include design and implementation of studies to examine the impact of IDILI drugs on homeostatic HDE signaling. Data collection will utilize cutting-edge imaging- and omics-based approaches as well as current molecular biology techniques. Translational work utilizing human biospecimens from the U.S Drug-Induced Liver Injury Network (DILIN) is also possible. These studies are supported by a collaboration between the IDSS (Dr. Paul Watkins and Dr. Merrie Mosedale) and a major pharmaceutical company. The successful candidate will have interactions with industry partners, as well as world class toxicologists, systems biologists, and cellular engineering experts at the UNC Eshelman School of Pharmacy. The project term is two years, and the experience should prepare the candidate for productive careers in academia, industry, or government.

Deadline: As soon as possible
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