Postdoctoral Postdoc Position at University of North Carolina Chapel Hill

A new postdoctoral position in biochemistry is available at University of North Carolina Chapel Hill. Applications will be evaluated on a continuous basis.

A POSTDOCTORAL POSITION is available to study the function and metabolism of glycerolipid metabolism as it relates to pancreatic beta-cell function. Applicants should have a recent PhD in physiology, biochemistry or a related field. Applicants should have a strong interest in mammalian lipid metabolism as it pertains to diabetes, an excellent publication record, and experience in one or more of the following topics: mouse energy metabolism and physiology, lipid biochemistry and metabolism, or rodent pancreatic islet physiology. Our current research asks what intracellular lipid metabolites alter insulin secretion, how intracellular lipids mediate insulin secretion, and how dietary fatty acids alter glucose homeostasis by directly impacting pancreatic beta-cell function. Applicants should be able to initiate new ideas, complete experimental studies independently, perform biochemical assays, supervise junior people in the lab, critique manuscripts, perform basic statistical calculations, prepare manuscripts and figures. Applicants should be able to read and interpret relevant literature.

Klett, EL, Chen, S, Edin, ML, Li, LO, Ilkayeva, O, Zeldin, DC, Newgard, CB, and Coleman, RA. Diminished acyl-CoA synthetase isoform 4 (Acsl4) activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion (2013) J. Biol. Chem. 2013 Jul 26;288(30):21618-29. PMID:23766516; PMCID: PMC3724621 Klett EL, Chen S, Yechoor A, Lih F, Coleman RA (2017) Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids. J Lipid Res. 58(5): 884-894. PMID 28209804. (Subject of a companion commentary- PMID 28242788).
Deadline: As soon as possible
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